"LY96" Related Products

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Recombinant Human Lymphocyte Antigen 96, His-tagged

Cat. No. : LY96-1548H
Product Overview : Recombinant Human LY96 was expressed inE.Coliusing an N-terminal His tag. MW= 22 kDa.
Description : MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.
Source : E.Coli.
Sequence : 1-160.
Purity : 95%.
Specific Activity : n/aH.
Applications : E, WB, MS.
Buffer : 1X PBS containing 0.1% SDS.
Storage : Store at -70?C. As with any protein, exposing LY96 recombinant protein to repeated freeze/thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
SDS-PAGE : SDS PAGE Analysis of LY96 Recombinant Protein. 4-20% SDS gradient gel. Coomassie blue staining.
Gene Name : LY96 lymphocyte antigen 96 [ Homo sapiens ]
Synonyms : LY96; lymphocyte antigen 96; MD2; MD-2; myeloid differentiation protein-2; MD-2 protein
Gene ID : 23643
mRNA Refseq : NM_015364
Protein Refseq : NP_056179
MIM : 605243
UniProt ID : Q9Y6Y9
Chromosome Location : 8q21.11
Pathway : Pathogenic Escherichia coli infection; Toll-like receptor signaling pathway; Signaling in Immune system
Function : coreceptor activity; lipopolysaccharide receptor activity; protein binding

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