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Recombinant Human DCTD, T7 -tagged

Cat.No.: DCTD-27369TH
Product Overview: Recombinant DCTD fusion protein (Human).Fusion: T7 tag at N-terminus.
Description: The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene.
Conjugation: T7
Source: E. coli
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: 0.002% Sodium AzideConstituents: 0.1% Triton X-100, 10mM Tris, pH 8.0
Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities: Belongs to the cytidine and deoxycytidylate deaminase family.
Gene Name: DCTD dCMP deaminase [ Homo sapiens ]
Official Symbol: DCTD
Synonyms: DCTD; dCMP deaminase; deoxycytidylate deaminase;
Gene ID: 1635
mRNA Refseq: NM_001012732
Protein Refseq: NP_001012750
MIM: 607638
Uniprot ID: P32321
Chromosome Location: 4q35.1
Pathway: Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Pyrimidine biosynthesis, organism-specific biosystem; Pyrimidine metabolism, organism-specific biosystem;
Function: dCMP deaminase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; metal ion binding; zinc ion binding;

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