| Description : |
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon. |
| Protein length : |
183 amino acids |
| Molecular Weight : |
46.200kDa inclusive of tags |
| Source : |
Wheat germ |
| Tissue specificity : |
Ubiquitous. |
| Form : |
Liquid |
| Purity : |
Proprietary Purification |
| Storage buffer : |
pH: 8.00Constituents:0.79% Tris HCl, 0.31% Glutathione |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : |
MQLVDHRGGGGGGGKGGRSRYRTTS SANNPNLMYQDECDRRLRGVKDGGR RDSASYRDRSETDRAGYANGSGYGS PNSAFGAQAGQYTYGQGTYGAAAYG TSSYTAQEYGAGTYGASSTTSTGRS SQSSSQQFSGIGRSGQQPQPLMSQQ FAQPPGATNMIGYMGQTAYQYPPPP PPPPPSRK |
| Sequence Similarities : |
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.Contains 1 helicase ATP-binding domain.Contains 1 helicase C-terminal domain. |
