Recombinant Human DLD, His-tagged DLD-29949TH

Recombinant Human DLD, His-tagged


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Recombinant Human DLD, His-tagged

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Cat.No. : DLD-29949TH
Product Overview : Recombinant full length Human Lipoamide Dehydrogenase fused to His tag at the N-terminus; 511 amino acids with tag, MWt 54.4kDa.
Description : This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.
Conjugation : HIS
Source : E. coli
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities : Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
Gene Name : DLD dihydrolipoamide dehydrogenase [ Homo sapiens ]
Official Symbol : DLD
Synonyms : DLD; dihydrolipoamide dehydrogenase; dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2 oxo glutarate complex, branched chain keto acid dehydrogenase complex) , GCSL, LAD; dihydrolipoyl dehydrogenase, mitochondrial; DLDH; E3
Gene ID : 1738
mRNA Refseq : NM_000108
Protein Refseq : NP_000099
MIM : 238331
Uniprot ID : P09622
Chromosome Location : 7q31-q32
Pathway : 2-ketoglutarate dehydrogenase complex, conserved biosystem; 2-oxobutanoate degradation I, conserved biosystem; Branched-chain amino acid catabolism, organism-specific biosystem; Citrate cycle (TCA cycle), organism-specific biosystem; Citrate cycle (TCA cycle), conserved biosystem;
Function : NAD binding; dihydrolipoyl dehydrogenase activity; flavin adenine dinucleotide binding; lipoamide binding; oxidoreductase activity;

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