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Recombinant Human DNAJB1

Cat.No. : DNAJB1-28381TH
Product Overview : Recombinant full length Human Hsp40 amino acids 1-340. Predicted MWt 38 kDa.
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  • Gene Information
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Description : Human HSP40 (heat shock protein with molecular size of 40kDa) is one of the mammalian homologues of bacterial DnaJ heat shock protein and regulates cellular processes by aiding in the folding, transport and assembly.
Protein length : 340 amino acids
Molecular Weight : 38.000kDa
Source : E. coli
Form : Liquid
Purity : >90% by SDS-PAGE
Storage buffer : Constituent:99% PBS
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Contains 1 J domain.
Gene Name : DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 [ Homo sapiens ]
Official Symbol : DNAJB1
Synonyms : DNAJB1; DnaJ (Hsp40) homolog, subfamily B, member 1; HSPF1; dnaJ homolog subfamily B member 1; Hsp40; radial spoke 16 homolog B (Chlamydomonas); RSPH16B; Sis1;
Gene ID : 3337
mRNA Refseq : NM_006145
Protein Refseq : NP_006136
MIM : 604572
Uniprot ID : P25685
Chromosome Location : 19p13.2
Pathway : Influenza A, organism-specific biosystem; Influenza A, conserved biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem;
Function : heat shock protein binding; unfolded protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does DNAJB1 contribute to the pathogenesis of neurodegenerative diseases, such as Alzheimer's and Parkinson's? 05/30/2022

DNAJB1 plays a role in neurodegenerative diseases by influencing the handling of misfolded proteins in neurons.

How does DNAJB1 influence the immune response, especially in regulating inflammation and immune cell function? 05/26/2021

DNAJB1 modulates the immune system, particularly in controlling inflammation and immune cell responses.

How does DNAJB1 assist in protein folding and prevent misfolding or aggregation of proteins within cells? 05/16/2021

DNAJB1 aids in protein folding and prevents the aggregation of misfolded proteins, crucial for maintaining cellular proteostasis.

What are the mechanisms by which DNAJB1 modulates apoptosis and cell survival under stress? 02/11/2021

DNAJB1 regulates apoptosis and cell survival, especially under conditions of cellular stress.

What is the impact of DNAJB1 on cancer cell survival, proliferation, and response to chemotherapy? 09/06/2019

DNAJB1 affects cancer cell behavior, influencing tumor growth, survival, and sensitivity to treatments.

What role does DNAJB1 play in cellular responses to heat shock and other stress conditions? 05/08/2019

DNAJB1 is key in cellular stress responses, particularly to heat shock, by stabilizing proteins and aiding in recovery.

How do alterations in DNAJB1 expression or function affect muscle cell health and the development of muscular disorders? 10/04/2018

Changes in DNAJB1 expression impact muscle cell function and health, potentially contributing to muscular disorders.

Customer Reviews (3)

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Reviews
07/15/2022

    Efficient peptide synthesis, crucial for advancing our peptide research.

    07/21/2021

      Exceptional protein engineering services, a vital resource for our lab.

      11/26/2020

        Reliable protein crystallography, a crucial part of structural research.

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