||Recombinant fragment, corresponding to amino acids 137-588 of Human E4F1 with an N terminal His tag. Predicted MWt: 50 kDa,
||The zinc finger protein encoded by this gene is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. A 50-kDa amino-terminal product is generated from the full-length protein through proteolytic cleavage. The protein is differentially regulated by E1A-induced phosphorylation. The full-length gene product represses transcription from the E4 promoter in the absence of E1A, while the 50-kDa form acts as a transcriptional activator in its presence.
||Lyophilised:Reconstitute with 87 μl aqua dest.
||Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
||Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
|Sequences of amino acids:
||LVGGGHIKEVIVAAEAELGDGEMAEAPGSPRQQGLGLAGE GEQAQVKLLVNKDGRYVCALCHKTFKTGSILKAHMVTH SSRKDHECKLCGASFRTKGSLIRHHRRHTDERPYKCSK CGKSFRESGALTRHLKSLTPCTEKIRFSVSKDVVVSKEDA RAGSGAGAAGLGTATSSVTGEPIETSPVIHLVTDAKGT VIHEVHVQMQELSLGMKALAPEPPVSQELPCSSEGSRE NLLHQAMQNSGIVLERAAGEEGALEPAPAAGSSPQPLA VAAPQLPVLEVQPLETQVASEASAVPRTHPCPQCSETFPT AATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKKHQEV HVRERRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCP KCGKRYKTKNAQQVHFRTHLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHG