Recombinant Human EEF1G, His-tagged

• Cat.No.: EEF1G-27778TH
• Product Overview: Recombinant full length protein, corresponding to amino acids 2-437 of Human EEF1G with N terminal His tag. Predicted MWt 50kDa

Specification

• Description: This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases.
• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Highly expressed in pancreatic tumor tissue and to a lesser extent in normal kidney, intestine, pancreas, stomach, lung, brain, spleen and liver.
• Form: Lyophilised:Reconstitute with 113 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: AAGTLYTYPENWRAFKALIAAQYSG AQVRVLSAPPHFHFG QTNRTPEFLRKFPAGKVPAFEGDDG FCVFESNAIAYYV SNEELRGSTPEAAAQVVQWVSFADS DIVPPASTWVFPT LGIMHHNKQATENAKEEVRRILGLL DAYLKTRTFLVGERV TLADITVVCTLLWLYKQVLEPSFRQ AFPNTNRWFLTCI NQPQFRAVLGEVKLCEKMAQFDAKK FAETQPKKDTPRK EKGSREEKQKPQAERKEEKKAAAPA PEEEMDECEQALAAEPKAKDPFAHL PKSTFVLDEFKRKYSNEDTLSVALP YFW EHFDKDGWSLWYSEYRFPEELTQTF MSCNLITGMFQRL DKLRKNAFASVILFGTNNSSSISGV WVFRGQELAFPLS PDWQVDYESYTWRKLDPGSEETQTL VREYFSWEGAFQHVG KAFNQGKIFK
• Sequence Similarities: Contains 1 EF-1-gamma C-terminal domain.Contains 1 GST C-terminal domain.Contains 1 GST N-terminal domain.

Gene Information

• Gene Name: EEF1G eukaryotic translation elongation factor 1 gamma [ Homo sapiens ]
• Official Symbol: EEF1G
• Synonyms: EEF1G; eukaryotic translation elongation factor 1 gamma; elongation factor 1-gamma; EF1G
• Gene ID: 1937
• mRNA Refseq: NM_001404
• Protein Refseq: NP_001395
• MIM: 130593
• Uniprot ID: P26641
• Chromosome Location: 11q12.3
• Pathway: Eukaryotic Translation Elongation, organism-specific biosystem; Gene Expression, organism-specific biosystem; Legionellosis, organism-specific biosystem; Legionellosis, conserved biosystem; Metabolism of proteins, organism-specific biosystem
• Function: protein binding; translation elongation factor activity