Recombinant Human EGR1
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Cat.No. : | EGR1-28467TH |
Product Overview : | Recombinant fragment correponding to amino acids 444-543 of Human Egr1 with an N terminal proprietary tag; Predicted MWt 36.63 kDa. |
Description : | The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. |
Protein length : | 100 amino acids |
Molecular Weight : | 36.630kDa inclusive of tags |
Source : | Wheat germ |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | SPVATSYPSP VTTSYPSPAT TSYPSPVPTS FSSPGSSTYP SPVHSGFPSP SVATTYSSVP PAFPAQVSSF PSSAVTNSFS ASTGLSDMTA TFSPRTIEIC |
Sequence Similarities : | Belongs to the EGR C2H2-type zinc-finger protein family.Contains 3 C2H2-type zinc fingers. |
Gene Name : | EGR1 early growth response 1 [ Homo sapiens ] |
Official Symbol : | EGR1 |
Synonyms : | EGR1; early growth response 1; early growth response protein 1; AT225; G0S30; KROX 24; nerve growth factor induced protein A; NGFI A; TIS8; transcription factor ETR103; ZIF 268; zinc finger protein 225; ZNF225; |
Gene ID : | 1958 |
mRNA Refseq : | NM_001964 |
Protein Refseq : | NP_001955 |
MIM : | 128990 |
Uniprot ID : | P18146 |
Chromosome Location : | 5q23-q31 |
Pathway : | Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Downstream signaling in naive CD8+ T cells, organism-specific biosystem; ErbB1 downstream signaling, organism-specific biosystem; Glucocorticoid receptor regulatory network, organism-specific biosystem; |
Function : | DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; double-stranded DNA binding; histone acetyltransferase binding; metal ion binding; |
◆ Recombinant Protein
EGR1-1384H | Recombinant Human EGR1 Protein (444-543 aa), His-tagged | +Inquiry |
EGR1-3121H | Recombinant Human EGR1 Protein, GST-tagged | +Inquiry |
EGR1-2841H | Recombinant Human EGR1 protein, His-B2M-tagged | +Inquiry |
EGR1-628H | Recombinant Human EGR1 Protein, His-tagged | +Inquiry |
EGR1-5712C | Recombinant Chicken EGR1 | +Inquiry |
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◆ Lysates
EGR1-6692HCL | Recombinant Human EGR1 293 Cell Lysate | +Inquiry |
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