Recombinant Human ELK3

• Cat.No.: ELK3-28287TH
• Product Overview: Recombinant fragment of Human ELK3 with N-terminal proprietary tag. Predicted MW 36.63kDa.

Specification

• Description: The protein encoded by this gene is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present.
• Protein length: 100 amino acids
• Molecular Weight: 36.630kDa inclusive of tags
• Source: Wheat germ
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: SRESLLLQDSDCKASPEGREAHKHG LAALRSTSRNEYIHSGLYSSFTINS LQNPPDAFKAIKTEKLEEPPEDSPP VEEVRTVIRFVTNKTDKHVTRPVVS
• Sequence Similarities: Belongs to the ETS family.Contains 1 ETS DNA-binding domain.

Gene Information

• Gene Name: ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) [ Homo sapiens ]
• Official Symbol: ELK3
• Synonyms: ELK3; ELK3, ETS-domain protein (SRF accessory protein 2); ETS domain-containing protein Elk-3; ERP; NET; SAP2
• Gene ID: 2004
• mRNA Refseq: NM_005230
• Protein Refseq: NP_005221
• MIM: 600247
• Uniprot ID: P41970
• Chromosome Location: 12q23
• Pathway: Id Signaling Pathway, organism-specific biosystem
• Function: protein binding; purine-rich negative regulatory element binding; sequence-specific DNA binding transcription factor activity; transcription corepressor activity