Recombinant Human CD226 Molecule
Cat.No. : | CD226-1603H |
- Specification
- Gene Information
- Related Products
Cat. No. : | CD226-1603H |
Description : | DNAX accessory molecule 1 (DNAM-1), is a tyrosine-phosphorylated signal-transducing molecule belonging to the immunoglobulin superfamily and participates in primary adhesion during cytotoxic T lymphocyte-mediated cytotoxicity. DNAM-1 is a functional glycoprotein expressed on immune cells, such as natural killer and T-cells. It is activated upon interaction with its biological ligands, the poliovirus receptor and nectin-2. Signaling cascades involving stimulation of DNAM-1 lead to various biological responses, including target cell lysis and immune cell activation. DNAM-1 appears to be an integral molecule in immune responses in cancer, allergic inflammatory disorders and autoimmune diseases. |
Molecular Weight : | The predicted molecular weight of Recombinant Human DNAM-1 is Mr 53 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 90 kDa. |
Source : | Mammalian cells |
State Of Matter : | Lyophilized. |
Purity : | >95% by SDS Page and analyzed by silver stain. |
Endotoxin : | <0.1 ng per 1 µg as determined by the LAL method. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | CD226 CD226 molecule [ Homo sapiens ] |
Synonyms : | CD226; CD226 molecule; PTA1; DNAM1; DNAM-1; TLiSA1; CD226 antigen; adhesion glycoprotein; DNAX accessory molecule-1; platelet and T cell activation antigen 1; T lineage-specific activation antigen 1 antigen |
Gene ID : | 10666 |
mRNA Refseq : | NM_006566 |
Protein Refseq : | NP_006557 |
MIM : | 605397 |
UniProt ID : | Q15762 |
Chromosome Location : | 18q22 |
Pathway : | adhesion molecules (CAMs) |
Function : | cell adhesion molecule binding; integrin binding; protein kinase binding; receptor activity |
Products Types
◆ Recombinant Protein | ||
Cd226-2056M | Recombinant Mouse Cd226 Protein, Myc/DDK-tagged | +Inquiry |
CD226-4374H | Recombinant Human CD226 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD226-395H | Recombinant Human CD226 Protein (Met1-Asn247), His-Fc-tagged, Biotinylated | +Inquiry |
CD226-3056H | Recombinant Human CD226 Protein, MYC/DDK-tagged | +Inquiry |
CD226-220H | Recombinant Human CD226 Protein, C-His-tagged | +Inquiry |
◆ Lysates | ||
CD226-1173RCL | Recombinant Rat CD226 cell lysate | +Inquiry |
CD226-2645HCL | Recombinant Human CD226 cell lysate | +Inquiry |
CD226-1167CCL | Recombinant Cynomolgus CD226 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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