Recombinant Human FBLN1
Cat.No. : | FBLN1-28904TH |
Product Overview : | Recombinant full length Human Fibulin 1 with N terminal proprietary tag; Predicted MWt 101.2 kDa inclusive of tag. |
- Specification
- Gene Information
- Related Products
Description : | Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3 end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants. |
Protein length : | 683 amino acids |
Molecular Weight : | 101.200kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Isoform A and isoform B are only expressed in placenta. Isoform C and isoform D are expressed in a variety of tissues and cultured cells. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MERAAPSRRVPLQLLLLGGLALLAAGVDADVLLEACCADG HRMATHQKDCSLPYATESKECRMVQEQCCHSQLEELHCAT GISLANEQDRCATPHGDNASLEATFVKRCCHCCLLGRAAQ AQGQSCEYSLMVGYQCGQVFRACCVKSQETGDLDVGGLQE TDKIIEVEEEQEDPYLNDRCRGGGPCKQQCRDTGDEVVCS CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSF RCQRDSSCGTGYELTEDNSCKDIDECESGIHNCLPDFICQ NTLGSFRCRPKLQCKSGFIQDALGNCIDINECLSISAPCP IGHTCINTEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDEC APPAEPCGKGHRCVNSPGSFRCECKTGYYFDGISRMCVDV NECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSCE DINECSSSPCSQECANVYGSYQCYCRRGYQLSDVDGVTCE DIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNG SNCQDIDECVTGIHNCSINETCFNIQGGFRCLAFECPENY RRSAATRCERLPCHENRECSKLPLRITYYHLSFPTNIQAP AVVFRMGPSSAVPGDSMQLAITGGNEEGFFTTRKVSPHSG VVALTKPVPEPRDLLLTVKMDLSRHGTVSSFVAKLFIFVS AEL |
Sequence Similarities : | Belongs to the fibulin family.Contains 3 anaphylatoxin-like domains.Contains 9 EGF-like domains. |
Gene Name : | FBLN1 fibulin 1 [ Homo sapiens ] |
Official Symbol : | FBLN1 |
Synonyms : | FBLN1; fibulin 1; fibulin-1; FBLN; |
Gene ID : | 2192 |
mRNA Refseq : | NM_001996 |
Protein Refseq : | NP_001987 |
MIM : | 135820 |
Uniprot ID : | P23142 |
Chromosome Location : | 22q13.31 |
Function : | calcium ion binding; extracellular matrix structural constituent; peptidase activator activity; |
Products Types
◆ Recombinant Protein | ||
Fbln1-726R | Recombinant Rat Fbln1 Protein, His/GST-tagged | +Inquiry |
FBLN1-2429H | Recombinant Human FBLN1 Protein (30-703 aa), His-Myc-tagged | +Inquiry |
FBLN1-3872H | Recombinant Human FBLN1 Protein, GST-tagged | +Inquiry |
FBLN1-723H | Recombinant Human FBLN1 Protein, His-tagged | +Inquiry |
FBLN1-1464H | Recombinant Human FBLN1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
FBLN1-598HCL | Recombinant Human FBLN1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionFBLN1 has been identified as a potential therapeutic target for the treatment of cardiovascular diseases due to its involvement in vascular function.
Genetic testing for FBLN1 mutations can be helpful in diagnosing certain connective tissue disorders.
The potential side effects of targeting FBLN1 as a therapeutic target are still under investigation and require further clinical trials.
FBLN1 has distinct roles and implications in clinical applications compared to other proteins, making it an important focus of research.
Mutations in the FBLN1 gene have been associated with developmental abnormalities in connective tissues, leading to connective tissue disorders such as Marfan syndrome and cutis laxa.
Customer Reviews (3)
Write a reviewThis partnership enhances research productivity while ensuring accurate and meaningful outcomes.
The manufacturer's commitment to maintaining stringent quality control measures guarantees that I can trust the protein's integrity and reliability throughout my experiments.
Its purity and stability ensure consistent and accurate results, making it an ideal tool for my research endeavors.
Ask a Question for All FBLN1 Products
Required fields are marked with *
My Review for All FBLN1 Products
Required fields are marked with *
Inquiry Basket