Recombinant Human FBLN1

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Recombinant Human FBLN1

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Cat.No. : FBLN1-28904TH
Product Overview : Recombinant full length Human Fibulin 1 with N terminal proprietary tag; Predicted MWt 101.2 kDa inclusive of tag.
Description : Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3 end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants.
Protein length : 683 amino acids
Molecular Weight : 101.200kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Isoform A and isoform B are only expressed in placenta. Isoform C and isoform D are expressed in a variety of tissues and cultured cells.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MERAAPSRRV PLQLLLLGGL ALLAAGVDAD VLLEACCADG HRMATHQKDC SLPYATESKE CRMVQEQCCH SQLEELHCAT GISLANEQDR CATPHGDNAS LEATFVKRCC HCCLLGRAAQ AQGQSCEYSL MVGYQCGQVF RACCVKSQET GDLDVGGLQE TDKIIEVEEE QEDPYLNDRC RGGGPCKQQC RDTGDEVVCS CFVGYQLLSD GVSCEDVNEC ITGSHSCRLG ESCINTVGSF RCQRDSSCGT GYELTEDNSC KDIDECESGI HNCLPDFICQ NTLGSFRCRP KLQCKSGFIQ DALGNCIDIN ECLSISAPCP IGHTCINTEG SYTCQKNVPN CGRGYHLNEE GTRCVDVDEC APPAEPCGKG HRCVNSPGSF RCECKTGYYF DGISRMCVDV NECQRYPGRL CGHKCENTLG SYLCSCSVGF RLSVDGRSCE DINECSSSPC SQECANVYGS YQCYCRRGYQ LSDVDGVTCE DIDECALPTG GHICSYRCIN IPGSFQCSCP SSGYRLAPNG SNCQDIDECV TGIHNCSINE TCFNIQGGFR CLAFECPENY RRSAATRCER LPCHENRECS KLPLRITYYH LSFPTNIQAP AVVFRMGPSS AVPGDSMQLA ITGGNEEGFF TTRKVSPHSG VVALTKPVPE PRDLLLTVKM DLSRHGTVSS FVAKLFIFVS AEL
Sequence Similarities : Belongs to the fibulin family.Contains 3 anaphylatoxin-like domains.Contains 9 EGF-like domains.
Gene Name : FBLN1 fibulin 1 [ Homo sapiens ]
Official Symbol : FBLN1
Synonyms : FBLN1; fibulin 1; fibulin-1; FBLN;
Gene ID : 2192
mRNA Refseq : NM_001996
Protein Refseq : NP_001987
MIM : 135820
Uniprot ID : P23142
Chromosome Location : 22q13.31
Function : calcium ion binding; extracellular matrix structural constituent; peptidase activator activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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