Recombinant Human FGD3, His-tagged

• Cat.No.: FGD3-27710TH
• Product Overview: Recombinant fragment, corresponding to amino acids 518-725 of Human FGD3 with N terminal His tag; Predicted MWt 24 kDa.

Specification

• Description: FYVE, RhoGEF and PH domain-containing protein 3 is a protein that in humans is encoded by the FGD3 gene.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 79 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: AGLEPRKLSSKTRRDKEKQSCKSCGETFNSITKRRHHCKL CGAVICGKCSEFKAENSRQSRVCRDCFLTQPVAPESTE KTPTADPQPSLLCGPLRLSESGETWSEVWAAIPMSDPQ VLHLQGGSQDGRLPRTIPLPSCKLSVPDPEERLDSGHV WKLQWAKQSWYLSASSAELQQQWLETLSTAAHGDTAQDSP GALQLQVPMGAAAP

Gene Information

• Gene Name: FGD3 FYVE, RhoGEF and PH domain containing 3 [ Homo sapiens ]
• Official Symbol: FGD3
• Synonyms: FGD3; FYVE, RhoGEF and PH domain containing 3; FGD1 family, member 3; FYVE, RhoGEF and PH domain-containing protein 3; FLJ00004; ZFYVE5
• Gene ID: 89846
• mRNA Refseq: NM_033086
• Protein Refseq: NP_149077
• Uniprot ID: Q5JSP0
• Chromosome Location: 9q22
• Pathway: Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; NRAGE signals death through JNK, organism-specific biosystem; Regulation of actin cytoskeleton, organism-specific biosystem
• Function: Rho guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; metal ion binding; small GTPase binding