Recombinant Human FGD3 Protein, GST-tagged

• Cat.No.: FGD3-4090H
• Product Overview: Human FGD3 full-length ORF ( AAH32429.1, 1 a.a. - 725 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: FGD3 (FYVE, RhoGEF And PH Domain Containing 3) is a Protein Coding gene. Diseases associated with FGD3 include Aarskog-Scott Syndrome and Scott Syndrome. Among its related pathways are p75 NTR receptor-mediated signalling and Signaling by GPCR. GO annotations related to this gene include guanyl-nucleotide exchange factor activity and small GTPase binding. An important paralog of this gene is FGD1.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 105.8 kDa
• AA Sequence: MESGRGSSTPPGPIAALGMPDTGPG SSSLGKLQALPVGPRAHCGDPVSLA AAGDGSPDIGPTGELSGSLKIPNRD SGIDSPSSSVAGENFPCEEGLEAGP SPTVLGAHAEMALDSQVPKVTPQEE ADSDVGEEPDSENTPQKADKDAGLA QHSGPQKLLHIAQELLHTEETYVKR LHLLDQVFCTRLTDAGIPPEVIMGI FSNISSIHRFHGQFLLPELKTRITE EWDTNPRLGDILQKLAPFLKMYGEY VKNFDRAVGLVSTWTQRSPLFKDVI HSIQKQEVCGNLTLQHHMLEPVQRV PRYELLLKDYLKRLPQDAPDRKDAE RSLELISTAANHSNAAIRKVEKMHK LLEVYEQLGGEEDIVNPANELIKEG QIQKLSAKNGTPQDRHLFLFNSMIL YCVPKLRLMGQKFSVREKMDISGLQ VQDIVKPNTAHTFIITGRKRSLELQ TRTEEEKKEWIQIIQATIEKHKQNS ETFKAFGGAFSQDEDPSLSPDMPIT STSPVEPVVTTEGSSGAAGLEPRKL SSKTRRDKEKQSCKSCGETFNSITK RRHHCKLCGAVICGKCSEFKAENSR QSRVCRDCFLTQPVAPESTEKTPTA DPQPSLLCGPLRLSESGETWSEVWA AIPMSDPQVLHLQGGSQDGRLPRTI PLPSCKLSVPDPEERLDSGHVWKLQ WAKQSWYLSASSAELQQQWLETLST AAHGDTAQDSPGALQLQVPMGAAAP
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FGD3 FYVE, RhoGEF and PH domain containing 3 [ Homo sapiens ]
• Official Symbol: FGD3
• Synonyms: FGD3; FYVE, RhoGEF and PH domain containing 3; FGD1 family, member 3; FYVE, RhoGEF and PH domain-containing protein 3; FLJ00004; ZFYVE5; faciogenital dysplasia 3; zinc finger FYVE domain-containing protein 5; MGC117260
• Gene ID: 89846
• mRNA Refseq: NM_001083536
• Protein Refseq: NP_001077005
• MIM: 617554
• UniProt ID: Q5JSP0