||Recombinant full length mature Human FGF1 with His tag produced in the endosperm tissue of barley grain ; 157 amino acids with tag, Predicted MWt 18.1 kDa.
||The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described.
||Bioactivity:The bioactivity was determined by dose-dependent effect of Human FGF1 on proliferation of BaF3 cells transfected with FGF receptor. ED50 for FGF1-26204TH lies in the range of 1.00-1.50 ng/ml.
||Lyophilised:Reconstitute the lyophilized protein in sterile water to a concentration of no less than 100 μg/ml. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
||>95% by SDS-PAGE
||Preservative: NoneConstituents: PBS, pH 7.2
||The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C.
||Belongs to the heparin-binding growth factors family.