Recombinant Human FGF1, His-tagged
Cat.No. : | FGF1-26204TH |
Product Overview : | Recombinant full length mature Human FGF1 with His tag produced in the endosperm tissue of barley grain ; 157 amino acids with tag, Predicted MWt 18.1 kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. |
Conjugation : | HIS |
Biological activity : | Bioactivity:The bioactivity was determined by dose-dependent effect of Human FGF1 on proliferation of BaF3 cells transfected with FGF receptor. ED50 for FGF1-26204TH lies in the range of 1.00-1.50 ng/ml. |
Form : | Lyophilised:Reconstitute the lyophilized protein in sterile water to a concentration of no less than 100 μg/ml. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: PBS, pH 7.2 |
Storage : | The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. |
Sequence Similarities : | Belongs to the heparin-binding growth factors family. |
Gene Name : | FGF1 fibroblast growth factor 1 (acidic) [ Homo sapiens ] |
Official Symbol : | FGF1 |
Synonyms : | FGF1; fibroblast growth factor 1 (acidic); FGFA; heparin-binding growth factor 1; AFGF; ECGF; ECGF beta; ECGFA; ECGFB; endothelial cell growth factor; alpha; beta; FGF alpha; GLIO703; HBGF1; heparin binding growth factor 1; |
Gene ID : | 2246 |
mRNA Refseq : | NM_000800 |
Protein Refseq : | NP_000791 |
MIM : | 131220 |
Uniprot ID : | P05230 |
Chromosome Location : | 5q31.3-q33.2 |
Pathway : | Downstream signaling of activated FGFR, organism-specific biosystem; FGF signaling pathway, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR1 ligand binding and activation, organism-specific biosystem; FGFR1b ligand binding and activation, organism-specific biosystem; |
Function : | S100 alpha binding; fibroblast growth factor receptor binding; growth factor activity; heparin binding; protein binding; |
Products Types
◆ Native Protein | ||
FGF1-33B | Active Native Bovine FGF1 | +Inquiry |
FGF1-26203TH | Native Human FGF1 | +Inquiry |
◆ Lysates | ||
FGF1-6252HCL | Recombinant Human FGF1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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