Recombinant Human FHL1 FHL1-28893TH

Recombinant Human FHL1

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Recombinant Human FHL1

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Cat.No. : FHL1-28893TH
Product Overview : Recombinant fragment corresponding to amino acids 23-120 of Human FHL1 with a proprietary tag; Predicted MWt 36.41 kDa inclusive of tag.
Description : This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.
Protein length : 98 amino acids
Molecular Weight : 36.410kDa
Source : Wheat germ
Tissue specificity : Isoform 1 is highly expressed in skeletal muscle and to a lesser extent in heart, placenta, ovary, prostate, testis, small intestine, colon and spleen. Expression is barely detectable in brain, lung, liver, kidney, pancreas, thymus and peripheral blood le
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.79% Tris HCl, 0.31% Glutathione
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : DGHHCCLKCFDKFCA NTCVECRKPIGADSK EVHYKNRFWHDTCFR CAKCLHPLANETFVA KDNKILCNKCTTRED SPKCKGCFKAIVAGD QNVEYKGT
Sequence Similarities : Contains 3 LIM zinc-binding domains.
Gene Name : FHL1 four and a half LIM domains 1 [ Homo sapiens ]
Official Symbol : FHL1
Synonyms : FHL1; four and a half LIM domains 1; four and a half LIM domains protein 1; bA535K18.1; FHL1B; FLH1A; Four and a half LIM domains 1; KYO T; LIM protein SLIMMER; MGC111107; SLIM1; XMPMA;
Gene ID : 2273
mRNA Refseq : NM_001159699
Protein Refseq : NP_001153171
MIM : 300163
Uniprot ID : Q13642
Chromosome Location : Xq26.3
Pathway : Delta-Notch Signaling Pathway, organism-specific biosystem;
Function : metal ion binding; molecular_function; protein binding; zinc ion binding;

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