Recombinant Human FHL1

• Cat.No.: FHL1-28893TH
• Product Overview: Recombinant fragment corresponding to amino acids 23-120 of Human FHL1 with a proprietary tag; Predicted MWt 36.41 kDa inclusive of tag.

Specification

• Description: This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.
• Protein length: 98 amino acids
• Molecular Weight: 36.410kDa
• Source: Wheat germ
• Tissue specificity: Isoform 1 is highly expressed in skeletal muscle and to a lesser extent in heart, placenta, ovary, prostate, testis, small intestine, colon and spleen. Expression is barely detectable in brain, lung, liver, kidney, pancreas, thymus and peripheral blood le
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.31% Glutathione
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: DGHHCCLKCFDKFCANTCVECRKPI GADSKEVHYKNRFWHDTCFRCAKCL HPLANETFVAKDNKILCNKCTTRED SPKCKGCFKAIVAGDQNVEYKGT
• Sequence Similarities: Contains 3 LIM zinc-binding domains.

Gene Information

• Gene Name: FHL1 four and a half LIM domains 1 [ Homo sapiens ]
• Official Symbol: FHL1
• Synonyms: FHL1; four and a half LIM domains 1; four and a half LIM domains protein 1; bA535K18.1; FHL1B; FLH1A; Four and a half LIM domains 1; KYO T; LIM protein SLIMMER; MGC111107; SLIM1; XMPMA
• Gene ID: 2273
• mRNA Refseq: NM_001159699
• Protein Refseq: NP_001153171
• MIM: 300163
• Uniprot ID: Q13642
• Chromosome Location: Xq26.3
• Pathway: Delta-Notch Signaling Pathway, organism-specific biosystem
• Function: metal ion binding; molecular_function; protein binding; zinc ion binding