"FRS2" Related Products

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Recombinant Human FRS2

Cat.No.: FRS2-28951TH
Product Overview: Recombinant fragment corresponding to amino acids 1-341 of Human FRS2 with a propreitary tag; predicted mwt: 63.14 kDa.
Description: Fibroblast growth factor receptor substrate 2 is a protein that in humans is encoded by the FRS2 gene.
Protein length: 341 amino acids
Molecular Weight: 63.140kDa inclusive of tags
Source: Wheat germ
Tissue specificity: Highly expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis.
Form: Liquid
Purity: Proprietary Purification
Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: Glutathione is reduced.
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids: MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNELGSGIMELTDTELILYTRKRDSVKWHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVERNNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTPKEEPSSIEDRDPQILLEPEGVKFVLGPTPVQKQLMEKEKLEQLGRDQVSGSGANNTEWDTGYDSDERRDAPSVNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQ
Sequence Similarities: Contains 1 IRS-type PTB domain.
Gene Name: FRS2 fibroblast growth factor receptor substrate 2 [ Homo sapiens ]
Official Symbol: FRS2
Synonyms: FRS2; fibroblast growth factor receptor substrate 2; FRS2A; FRS2alpha; SNT 1; SNT1;
Gene ID: 10818
mRNA Refseq: NM_001042555
Protein Refseq: NP_001036020
MIM: 607743
Uniprot ID: Q8WU20
Chromosome Location: 12q15
Pathway: Downstream signaling of activated FGFR, organism-specific biosystem; FGF signaling pathway, organism-specific biosystem; FRS2-mediated cascade, organism-specific biosystem; Frs2-mediated activation, organism-specific biosystem; IRS-mediated signalling, organism-specific biosystem;
Function: fibroblast growth factor receptor binding; insulin receptor binding; phosphatase activator activity; protein binding; transmembrane receptor protein tyrosine kinase adaptor activity;

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