Recombinant Human GCNT1

• Cat.No.: GCNT1-27452TH
• Product Overview: Recombinant full length Human GCNT1 with N-terminal proprietary tag. Predicted MW 73.15kDa.

Specification

• Description: This gene is a member of the beta-1,6-N-acetylglucosaminyltransferase gene family. It is essential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures and the core 2 O-glycan branch. The gene coding this enzyme was originally mapped to 9q21, but was later localized to 9q13. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Protein length: 428 amino acids
• Molecular Weight: 73.150kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Highly expressed in activated T-lymphocytes and myeloid cells.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MLRTLLRRRLFSYPTKYYFMVLVLSLITFSVLRIHQKPEF VSVRHLELAGENPSSDINCTKVLQGDVNEIQKVKLEILTV KFKKRPRWTPDDYINMTSDCSSFIKRRKYIVEPLSKEEAE FPIAYSIVVHHKIEMLDRLLRAIYMPQNFYCIHVDTKSED SYLAAVMGIASCFSNVFVASRLESVVYASWSRVQADLNCM KDLYAMSANWKYLINLCGMDFPIKTNLEIVRKLKLLMGEN NLETERMPSHKEERWKKRYEVVNGKLTNTGTVKMLPPLET PLFSGSAYFVVSREYVGYVLQNEKIQKLMEWAQDTYSPDE YLWATIQRIPEVPGSLPASHKYDLSDMQAVARFVKWQYFE GDVSKGAPYPPCDGVHVRSVCIFGAGDLNWMLRKHHLFAN KFDVDVDLFAIQCLDEHLRHKALETLKH
• Sequence Similarities: Belongs to the glycosyltransferase 14 family.

Gene Information

• Gene Name: GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 [ Homo sapiens ]
• Official Symbol: GCNT1
• Synonyms: GCNT1; glucosaminyl (N-acetyl) transferase 1, core 2; glucosaminyl (N acetyl) transferase 1, core 2 (beta 1,6 N acetylglucosaminyltransferase) , NACGT2; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase; beta 1; 3 galact
• Gene ID: 2650
• mRNA Refseq: NM_001097633
• Protein Refseq: NP_001091102
• MIM: 600391
• Uniprot ID: Q02742
• Chromosome Location: 9q13
• Pathway: Metabolic pathways, organism-specific biosystem; Mucin type O-Glycan biosynthesis, organism-specific biosystem; Mucin type O-Glycan biosynthesis, conserved biosystem; O-glycan biosynthesis, mucin type core, organism-specific biosystem; O-glycan biosynthesis, mucin type core, conserved biosystem
• Function: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity; transferase activity, transferring glycosyl groups