Recombinant Human GCNT1, GST-tagged

• Cat.No.: GCNT1-13198H
• Product Overview: Recombinant Human GCNT1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 41-428a.a.
• Description: This gene encodes a member of a family of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases, which catalyze the transfer of N-acetylgalactosamine (GalNAc) from UDP-GalNAc to a serine or threonine residue on a polypeptide acceptor in the initial step of O-linked protein glycosylation. Mutations in this gene are associated with an increased susceptibility to colorectal cancer.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 [ Homo sapiens ]
• Official Symbol: GCNT1
• Synonyms: GCNT1; glucosaminyl (N-acetyl) transferase 1, core 2; glucosaminyl (N acetyl) transferase 1, core 2 (beta 1,6 N acetylglucosaminyltransferase) , NACGT2; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase; beta 1; 3 galactosyl O glycosyl glycoprotein beta 1; 6 N acetylglucosaminyltransferase; C2GNT; core 2 beta1; 6 N acetylglucosaminyltransferase I; NAGCT2; core 2 GnT; core 2 branching enzyme; core 2-branching enzyme; core2-GlcNAc-transferase; beta-1,6-N-acetylglucosaminyltransferase; core 2 beta1,6 N-acetylglucosaminyltransferase-I; core 2 beta-1,6-N-acetylglucosaminyltransferase I; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N--acetylglucosaminyltransferase; glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase); G6NT; C2GNT1; NACGT2; C2GNT-L; MGC126335; MGC126336
• Gene ID: 2650
• mRNA Refseq: NM_001097633
• Protein Refseq: NP_001091102
• MIM: 600391
• UniProt ID: Q02742
• Chromosome Location: 9q13
• Pathway: Metabolic pathways, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Mucin type O-Glycan biosynthesis, organism-specific biosystem; Mucin type O-Glycan biosynthesis, conserved biosystem; O-glycan biosynthesis, mucin type core, organism-specific biosystem; O-glycan biosynthesis, mucin type core, conserved biosystem; O-linked glycosylation of mucins, organism-specific biosystem
• Function: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity; transferase activity, transferring glycosyl groups