Recombinant Human GDF7 protein
Cat.No. : | GDF7-28992TH |
Product Overview : | Recombinant Human GDF7 protein was expressed in Escherichia coli. |
- Specification
- Gene Information
- Related Products
Description : | Growth/differentiation factors (GDF-1 to GDF-15) are members of the BMP family of TGF-beta superfamily proteins. They are produced as inactive preproproteins which are then cleaved and assembled into active secreted homodimers. GDF dimers are disulfide-linked with the exception of GDF-3 and -9. GDF proteins are important during embryonic development, particularly in the skeletal, nervous, and muscular systems. |
Source : | E.coli |
Species : | Human |
Form : | Lyophilized from a 0.2μm filtered concentrated solution in 30 % Acetonitrile and 0.1 % TFA. |
Bio-activity : | Fully biologically active when compared to standard. The ED50 as determined by inducing alkaline phosphatase production of murine ATDC5 cells is less than 1.0 μg/ml, corresponding to a specific activity of > 1000 IU/mg. |
Molecular Mass : | Approximately 28.0 kDa, a disulfide-linked homodimeric protein containing two 129 amino acids. |
Protein length : | 129 |
AA Sequence : | TALAGTRTAQGSGGGAGRGHGRRGR SRCSRKPLHVDFKELGWDDWIIAPL DYEAYHCEGLCDFPLRSHLEPTNHA IIQTLLNSMAPDAAPASCCVPARLS PISILYIDAANNVVYKQYEDMVVEA CGCR |
Endotoxin : | Less than 0.1 EU/µg of rHuGDF-7/BMP-12 as determined by LAL method. |
Purity : | >95% by SDS-PAGE and HPLC analysis. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions. |
Gene Name : | GDF7 |
Official Symbol : | GDF7 |
Synonyms : | GDF7; growth differentiation factor 7; growth/differentiation factor 7; BMP12; GDF-7; |
Gene ID : | 151449 |
mRNA Refseq : | NM_182828 |
Protein Refseq : | NP_878248 |
MIM : | 604651 |
UniProt ID : | Q7Z4P5 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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