Recombinant Human GPD2, His-tagged

• Cat.No.: GPD2-28583TH
• Product Overview: Recombinant human GPD2 comprises a 558 amino acid fragment (43-600) corresponding to the GlpA domain fragment of the mature GPD2 protein, with an amino-terminal hexahistidine tag.

Specification

• Description: The protein encoded by this gene localizes to the inner mitochondrial membrane and catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as a cofactor. Along with GDP1, the encoded protein constitutes the glycerol phosphate shuttle, which reoxidizes NADH formed during glycolysis. Two transcript variants encoding the same protein have been found for this gene.
• Conjugation: HIS
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 50% Glycerol, PBS
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.Contains 2 EF-hand domains.

Gene Information

• Gene Name: GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) [ Homo sapiens ]
• Official Symbol: GPD2
• Synonyms: GPD2; glycerol-3-phosphate dehydrogenase 2 (mitochondrial); glycerol-3-phosphate dehydrogenase, mitochondrial
• Gene ID: 2820
• mRNA Refseq: NM_000408
• Protein Refseq: NP_000399
• MIM: 138430
• Uniprot ID: P43304
• Chromosome Location: 2q24.1
• Pathway: Fatty Acid Beta Oxidation, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Glycerophospholipid metabolism, organism-specific biosystem; Glycerophospholipid metabolism, conserved biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem
• Function: calcium ion binding; glycerol-3-phosphate dehydrogenase [NAD+] activity; glycerol-3-phosphate dehydrogenase activity; oxidoreductase activity; sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity