Recombinant Human GRB7
Cat.No. : | GRB7-27926TH |
Product Overview : | Recombinant full length Human GRB7 with N terminal proprietary tag; Predicted MW 84.59 kDa. |
- Specification
- Gene Information
- Related Products
Description : | The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. |
Protein length : | 532 amino acids |
Molecular Weight : | 84.590kDa inclusive of tags |
Source : | Wheat germ |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVK RSQPLLIPTTGRKLREEERRATSLPSIPNPFPELCSPPSQ SPILGGPSSARGLLPRDASRPHVVKVYSEDGACRSVEVAA GATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLED HESVVEVQAAWPVGGDSRFVFRKNFAKYELFKSSPHSLFP EKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRG SGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNE SNVYVVTQGRKLYGMPTDFGFCVKPNKLRNGHKGLRIFCS EDEQSRTCWLAAFRLFKYGVQLYKNYQQAQSRHLHPSCLG SPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQ AWRKKTNHRLSLPMPASGTSLSAAIHRTQLWFHGRISREE SQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHY LILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILP CLLRHCCTRVAL |
Sequence Similarities : | Belongs to the GRB7/10/14 family.Contains 1 PH domain.Contains 1 Ras-associating domain.Contains 1 SH2 domain. |
Gene Name : | GRB7 growth factor receptor-bound protein 7 [ Homo sapiens ] |
Official Symbol : | GRB7 |
Synonyms : | GRB7; growth factor receptor-bound protein 7; |
Gene ID : | 2886 |
mRNA Refseq : | NM_001030002 |
Protein Refseq : | NP_001025173 |
MIM : | 601522 |
Uniprot ID : | Q14451 |
Chromosome Location : | 17q12 |
Pathway : | Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Downstream signal transduction, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; EPHB forward signaling, organism-specific biosystem; |
Function : | RNA binding; SH3/SH2 adaptor activity; identical protein binding; lipid binding; phosphatidylinositol binding; |
Products Types
◆ Recombinant Protein | ||
Grb7-1055M | Recombinant Mouse Grb7 Protein, MYC/DDK-tagged | +Inquiry |
GRB7-2341R | Recombinant Rat GRB7 Protein, His (Fc)-Avi-tagged | +Inquiry |
GRB7-3914M | Recombinant Mouse GRB7 Protein, His (Fc)-Avi-tagged | +Inquiry |
Grb7-248M | Recombinant Mouse Grb7 Protein, His-tagged | +Inquiry |
GRB7-247H | Recombinant Human GRB7 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
GRB7-5754HCL | Recombinant Human GRB7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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