Recombinant Human GRHPR, His-tagged

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Recombinant Human GRHPR, His-tagged

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Cat.No. : GRHPR-28538TH
Product Overview : Recombinant full length Human GRHPR with N terminal His tag; amino acids 1-328 , 37.8kDa.
Description : This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene.
Protein length : 328 amino acids
Conjugation : HIS
Molecular Weight : 37.800kDa inclusive of tags
Source : E. coli
Tissue specificity : Ubiquitous. Most abundantly expressed in the liver.
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 20% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, pH 8.0
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MRPVRLMKVF VTRRIPAEGR VALARAADCE VEQWDSDEPI PAKELERGVA GAHGLLCLLS DHVDKRILDA AGANLKVIST MSVGIDHLAL DEIKKRGIRV GYTPDVLTDT TAELAVSLLL TTCRRLPEAI EEVKNGGWTS WKPLWLCGYG LTQSTVGIIG LGRIGQAIAR RLKPFGVQRF LYTGRQPRPE EAAEFQAEFV STPELAAQSD FIVVACSLTP ATEGLCNKDF FQKMKETAVF INISRGDVVN QDDLYQALAS GKIAAAGLDV TSPEPLPTNH PLLTLKNCVI LPHIGSATHR TRNTMSLLAA NNLLAGLRGE PMPSELKL
Sequence Similarities : Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Gene Name : GRHPR glyoxylate reductase/hydroxypyruvate reductase [ Homo sapiens ]
Official Symbol : GRHPR
Synonyms : GRHPR; glyoxylate reductase/hydroxypyruvate reductase; GLXR; PH2; primary hyperoxaluria type 2;
Gene ID : 9380
mRNA Refseq : NM_012203
Protein Refseq : NP_036335
MIM : 604296
Uniprot ID : Q9UBQ7
Chromosome Location : 9q12
Pathway : Glyoxylate and dicarboxylate metabolism, organism-specific biosystem; Glyoxylate and dicarboxylate metabolism, conserved biosystem; Glyoxylate metabolism, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem;
Function : NAD binding; cofactor binding; glycerate dehydrogenase activity; glyoxylate reductase (NADP) activity; glyoxylate reductase (NADP) activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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