Recombinant Human GTF2B, His-tagged

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Recombinant Human GTF2B, His-tagged

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Cat.No. : GTF2B-30661TH
Product Overview : Recombinant full length Human TFIIB with N terminal His tag; 336 amino acids with tag, MWt 36.9kDa.
Description : This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.
Conjugation : HIS
Molecular Weight : 36.900kDa inclusive of tags
Source : E. coli
Form : Liquid
Purity : >90% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 20% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, pH 8.0
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MASTSRLDAL PRVTCPNHPD AILVEDYRAG DMICPECGLV VGDRVIDVGS EWRTFSNDKA TKDPSRVGDS QNPLLSDGDL STMIGKGTGA ASFDEFGNSK YQNRRTMSSS DRAMMNAFKE ITTMADRINL PRNIVDRTNN LFKQVYEQKS LKGRANDAIA SACLYIACRQ EGVPRTFKEI CAVSRISKKE IGRCFKLILK ALETSVDLIT TGDFMSRFCS NLCLPKQVQM AATHIARKAV ELDLVPGRSP ISVAAAAIYM ASQASAEKRT QKEIGDIAGV ADVTIRQSYR LIYPRAPDLF PTDFKFDTPV DKLPQL
Sequence Similarities : Belongs to the TFIIB family.Contains 1 TFIIB-type zinc finger.
Gene Name : GTF2B general transcription factor IIB [ Homo sapiens ]
Official Symbol : GTF2B
Synonyms : GTF2B; general transcription factor IIB; transcription initiation factor IIB; TFIIB;
Gene ID : 2959
mRNA Refseq : NM_001514
Protein Refseq : NP_001505
MIM : 189963
Uniprot ID : Q00403
Chromosome Location : 1p22-p21
Pathway : Basal transcription factors, organism-specific biosystem; Basal transcription factors, conserved biosystem; Eukaryotic Transcription Initiation, organism-specific biosystem; Formation and Maturation of mRNA Transcript, organism-specific biosystem; Gene Expression, organism-specific biosystem;
Function : DNA binding; metal ion binding; protein binding; thyroid hormone receptor binding; transcription factor binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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