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Recombinant Mouse Eph Receptor B3

Cat. No.: Ephb3-1728M
Description: Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.
Molecular Weight: The predicted molecular weight of Recombinant Mouse EphB3 is Mr 82.8 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 100 kDa.
Source: NSO Cells.
State Of Matter: Lyophilized.
Purity: >95% by SDS Page and analyzed by silver stain.
Endotoxin: <0.1 ng per 1 µg as determined by the LAL method.
Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name: Ephb3 Eph receptor B3 [ Mus musculus ]
Synonyms: Ephb3; Eph receptor B3; Etk2; HEK2; MDK5; Sek4; Cek10; Tyro6; AW456895; EC 2.7.10.1
Gene ID: 13845
mRNA Refseq: NM_010143
Protein Refseq: NP_034273
UniProt ID: P54754
Chromosome Location: 16 B1-B4
Pathway: Axon guidance
Function: ATP binding; axon guidance receptor activity; ephrin receptor activity; kinase activity; nucleotide binding; protein binding; protein kinase activity; protein tyrosine kinase activity; receptor activity; transferase activity; transmembrane receptor protein tyrosine kinase activity; transmembrane-ephrin receptor activity

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