Recombinant Mouse Eph Receptor B4, Fc-His
Cat.No. : | Ephb4-1729M |
Product Overview : | Recombinant Mouse EphB4 (Leu16 - Ala539) produced inNSO Cellswas fused to Fc region of human IgG1 (Pro100-Lys330) - 6xHis tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Ephb4-1729M |
Description : | Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. |
Molecular Weight : | The predicted molecular weight of Recombinant Mouse EphB4 is Mr 85.2 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 110 kDa. |
Source : | Mammalian cells |
State Of Matter : | Lyophilized. |
Purity : | >95% by SDS Page and analyzed by silver stain. |
Formulation : | This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives. |
Endotoxin : | <0.1 ng per 1 µg as determined by the LAL method. |
Biological Activity : | The biological activity of Mouse EphB4 was determined by its binding ability in a functional ELISA. Immobilized recombinant mouse EphB4 at 2 μg/ml (100 μl/well) can bind recombinant mouse EphrinB2 with a linear range of 0.078-5 ng/ml. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | Ephb4 Eph receptor B4 [ Mus musculus ] |
Synonyms : | Ephb4; Eph receptor B4; Htk; MDK2; Myk1; Tyro11; AI042935; OTTMUSP00000024612 |
Gene ID : | 13846 |
mRNA Refseq : | NM_001159571 |
Protein Refseq : | NP_001153043 |
UniProt ID : | P54761 |
Chromosome Location : | 5 G2 |
Pathway : | Axon guidance |
Function : | ATP binding; ephrin receptor activity; kinase activity; nucleotide binding; protein binding; protein kinase activity; protein tyrosine kinase activity; receptor activity; transferase activity; transmembrane receptor protein tyrosine kinase activity |
Products Types
◆ Recombinant Protein | ||
Ephb4-958M | Recombinant Mouse Ephb4 Protein, MYC/DDK-tagged | +Inquiry |
Ephb4-161M | Recombinant Mouse Ephb4 Protein, His (Fc)-Avi-tagged | +Inquiry |
EPHB4-227H | Recombinant Human EPHB4 Protein, His-tagged, Biotinylated | +Inquiry |
EPHB4-853H | Recombinant Human EPHB4 Protein, His (Fc)-Avi-tagged | +Inquiry |
EPHB4-3403H | Active Recombinant Human EPHB4 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
EPHB4-2128MCL | Recombinant Mouse EPHB4 cell lysate | +Inquiry |
EPHB4-2970HCL | Recombinant Human EPHB4 cell lysate | +Inquiry |
EPHB4-001HCL | Recombinant Human EPHB4 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1548 | U2OS EphB4 Bioassay Kit | +Inquiry |
Kit-1585 | EphB4 Functional Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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