Recombinant Human HEXIM1, His-tagged

• Cat.No.: HEXIM1-27730TH
• Product Overview: Recombinant full-length Human HEXIM1 fused to a 37 amino acid His-Tag and DDDDK-Tag at the N-Terminus, predicted MWt 44.8kDa.

Specification

• Description: Expression of this gene is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This gene has no introns.
• Protein length: 359 amino acids
• Conjugation: HIS
• Molecular Weight: 44.800kDa inclusive of tags
• Source: E. coli
• Tissue specificity: Ubiquitously expressed with higher expression in placenta. HEXIM1 and HEXIM2 are differentially expressed. Expressed in endocrine tissues.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:0.58% Sodium chloride, 10% Glycerol, 0.32% Tris HCl
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequences of amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAE PFLSEYQHQP QTSNCTGAAA VQEELNPERP PGAEERVPEE DSRWQSRAFP QLGGRPGPEG EGSLESQPPP LQTQACPESS CLREGEKGQN GDDSSAGGDF PPPAEVEPTP EAELLAQPCH DSEASKLGAP AAGGEEEWGQ QQRQLGKKKH RRRPSKKKRH WKPYYKLTWE EKKKFDEKQS LRASRIRAEM FAKGQPVAPY NTTQFLMDDH DQEEPDLKTG LYSKRAAAKS DDTSDDDFME EGGEEDGGSD GMGGDGSEFL QRDFSETYER YHTESLQNMS KQELIKEYLE LEKCLSRMED ENNRLRLESK RLGGDDARVR ELELELDRLR AENLQLLTEN ELHRQQERAP LSKFGD
• Sequence Similarities: Belongs to the HEXIM family.

Gene Information

• Gene Name: HEXIM1 hexamethylene bis-acetamide inducible 1 [ Homo sapiens ]
• Official Symbol: HEXIM1
• Synonyms: HEXIM1; hexamethylene bis-acetamide inducible 1; protein HEXIM1; CLP 1; EDG1; HIS1; MAQ1
• Gene ID: 10614
• mRNA Refseq: NM_006460
• Protein Refseq: NP_006451
• MIM: 607328
• Uniprot ID: O94992
• Chromosome Location: 17q21.31
• Function: cyclin-dependent protein kinase inhibitor activity; protein binding; snRNA binding