Recombinant Human HIC1 HIC1-29312TH

Recombinant Human HIC1


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Recombinant Human HIC1

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Cat.No. : HIC1-29312TH
Product Overview : Recombinant fragment corresponding to amino acids 627-705 of Human HIC1 with N terminal proprietary tag; Predicted MWt 34.32 kDa.
Description : This gene functions as a growth regulatory and tumor repressor gene. Hypermethylation or deletion of the region of this gene have been associated with tumors and the contiguous-gene syndrome, Miller-Dieker syndrome. Alternative splicing of this gene results in multiple transcript variants.
Protein length : 79 amino acids
Molecular Weight : 34.320kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Ubiquitously expressed with highest levels found in lung, colon, prostate, thymus, testis and ovary. Expression is absent or decreased in many tumor cells.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the krueppel C2H2-type zinc-finger protein family. Hic subfamily.Contains 1 BTB (POZ) domain.Contains 5 C2H2-type zinc fingers.
Gene Name : HIC1 hypermethylated in cancer 1 [ Homo sapiens ]
Official Symbol : HIC1
Synonyms : HIC1; hypermethylated in cancer 1; hypermethylated in cancer 1 protein; ZBTB29; ZNF901;
Gene ID : 3090
mRNA Refseq : NM_001098202
Protein Refseq : NP_001091672
MIM : 603825
Uniprot ID : Q14526
Chromosome Location : 17p13.3
Pathway : Direct p53 effectors, organism-specific biosystem; E2F transcription factor network, organism-specific biosystem;
Function : DNA binding; histone deacetylase binding; metal ion binding; protein binding; sequence-specific DNA binding;

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