"HMGB1" Related Products

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Recombinant Human HMGB1

Cat.No.: HMGB1-29334TH
Product Overview: Recombinant full length Human HMGB1, 233 amino acids, 25kDa, transfected in Baculovirus and expressed in High 5 cells.
Description: High-mobility group protein B1, also known as high-mobility group protein 1 (HMG-1) and amphoterin, is a protein that in humans is encoded by the HMGB1 gene.
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris, 1mM EDTA, 0.5mM DTT, pH 8
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequences of amino acids: MGKGDPKKPR GKMSSYAFFV QTCREEHKKK HPDASVNFSE FSKKCSERWKTMSAKEKGKF EDMAKADKAR YEREMKTYIP PKGETKKKFK DPNAPKRPPSAFFLFCSEYR PKIKGEHPGL SIGDVAKKLG EMWNNTAADD KQPYEKKAAKLKEKYEKDIA AYRAKGKPDA AKKGVVKAEK SKKKKEEEED EEDEEDEEEEEDEEDEDEEE DDDDELEHHH HHH
Sequence Similarities: Belongs to the HMGB family.Contains 2 HMG box DNA-binding domains.
Gene Name: HMGB1 high mobility group box 1 [ Homo sapiens ]
Official Symbol: HMGB1
Synonyms: HMGB1; high mobility group box 1; high mobility group (nonhistone chromosomal) protein 1 , high mobility group box 1 , HMG1; high mobility group protein B1; Amphoterin; DKFZp686A04236; high mobility group protein 1; HMG3; SBP 1; Sulfoglucuronyl carbohydr
Gene ID: 3146
mRNA Refseq: NM_002128
Protein Refseq: NP_002119
MIM: 163905
Uniprot ID: P09429
Chromosome Location: 13q12
Pathway: Activated TLR4 signalling, organism-specific biosystem; Activation of DNA fragmentation factor, organism-specific biosystem; Advanced glycosylation endproduct receptor signaling, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem;
Function: DNA bending activity; DNA bending activity; DNA binding; RAGE receptor binding; calcium-dependent protein kinase regulator activity;

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