Recombinant Human HNF1B
Cat.No. : | HNF1B-29461TH |
Product Overview : | Recombinant fragment of Human TCF2 with N terminal proprietary tag; Predicted MW 37.29kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene. |
Protein length : | 105 amino acids |
Molecular Weight : | 37.290kDa inclusive of tags |
Source : | Wheat germ |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | VRKQREILRQFNQTVQSSGNMTDKSSQDQLLFLFPEFSQQ SHGPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDR QKNPSKEEREALVEECNRAECLQRG |
Sequence Similarities : | Belongs to the HNF1 homeobox family.Contains 1 homeobox DNA-binding domain. |
Gene Name : | HNF1B HNF1 homeobox B [ Homo sapiens ] |
Official Symbol : | HNF1B |
Synonyms : | HNF1B; HNF1 homeobox B; TCF2, transcription factor 2, hepatic; LF B3; variant hepatic nuclear factor; hepatocyte nuclear factor 1-beta; HNF1beta; LFB3; MODY5; VHNF1; |
Gene ID : | 6928 |
mRNA Refseq : | NM_000458 |
Protein Refseq : | NP_000449 |
MIM : | 189907 |
Uniprot ID : | P35680 |
Chromosome Location : | 17q12 |
Pathway : | Developmental Biology, organism-specific biosystem; Maturity onset diabetes of the young, organism-specific biosystem; Maturity onset diabetes of the young, conserved biosystem; Regulation of beta-cell development, organism-specific biosystem; Regulation of gene expression in early pancreatic precursor cells, organism-specific biosystem; |
Function : | DNA binding; protein binding; protein heterodimerization activity; protein homodimerization activity; protein homodimerization activity; |
Products Types
◆ Recombinant Protein | ||
HNF1B-4892H | Recombinant Human HNF1B Protein, GST-tagged | +Inquiry |
HNF1B-1936R | Recombinant Rhesus Macaque HNF1B Protein, His (Fc)-Avi-tagged | +Inquiry |
HNF1B-2532R | Recombinant Rat HNF1B Protein, His (Fc)-Avi-tagged | +Inquiry |
Hnf1b-6335M | Recombinant Mouse Hnf1b Protein, Myc/DDK-tagged | +Inquiry |
HNF1B-4254M | Recombinant Mouse HNF1B Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
HNF1B-5460HCL | Recombinant Human HNF1B 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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