Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human GDNF Family Receptor Alpha 2

Cat.No. : GFRA2-1619H
  • Specification
  • Gene Information
  • Related Products
Cat. No. : GFRA2-1619H
Description : Glial cell line-derived neurotrophic factor family receptor alpha-2, also known as GFRA2, is the cognate co-receptor for the neurotrophic factor neurturin that is selectively expressed by isolectin B(4) (IB 4)-binding nociceptive sensory neurons. GFRA2 is required for the development of the myenteric nerve plexus and is an excellent candidate gene for Hirschsprung disease (HSCR). GFRalpha2 signaling is also needed for development of the parasympathetic islet innervation that is critical for vagally induced hormone secretion.
Source : Mammalian cells
Molecular Weight : The predicted molecular weight of Recombinant Human GFRα-2 is 74 kDa. However, the actual molecular weight as observed by migration on SDS Page is 100 kDa.
State Of Matter : Lyophilized.
Purity : >95% by SDS Page and analyzed by silver stain.
Endotoxin : <0.1 ng per 1 µg as determined by the LAL method.
Storage : This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name : GFRA2 GDNF family receptor alpha 2 [ Homo sapiens ]
Synonyms : GFRA2; GDNF family receptor alpha 2; NTNRA; RETL2; TRNR2; GDNFRB; NRTNR-ALPHA; NTNR-alpha; GDNF receptor beta; GDNFR-beta
Gene ID : 2675
mRNA Refseq : NM_001165038
Protein Refseq : NP_001158510
MIM : 601956
UniProt ID : O00451
Chromosome Location : 8p21.3
Pathway : Axon guidance
Function : glial cell line-derived neurotrophic factor receptor activity; receptor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All GFRA2 Products

Required fields are marked with *

My Review for All GFRA2 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends