"HTR7" Related Products

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Recombinant Human HTR7, T7 -tagged

Cat.No.: HTR7-26031TH
Product Overview: Recombinant full length Human 5HT7 Receptor with proprietary tag; Predicted MWt 73.59 kDa.
Description: The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends.
Protein length: 432 amino acids
Conjugation: T7
Molecular Weight: 73.590kDa inclusive of tags
Source: Wheat germ
Tissue specificity: Isoform A is the predominant isoform in spleen, caudate and hippocampus. Isoform B is expressed at lower levels. Isoform D is a minor isoform in term of expression.
Biological activity: useful for Antibody Production and Protein Array
Form: Liquid
Purity: Proprietary Purification
Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: Glutathione is reduced
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids: MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVL
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.
Gene Name: HTR7 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled) [ Homo sapiens ]
Official Symbol: HTR7
Synonyms: HTR7; 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled); 5-hydroxytryptamine receptor 7; 5 HT7;
Gene ID: 3363
mRNA Refseq: NM_000872
Protein Refseq: NP_000863
MIM: 182137
Uniprot ID: P34969
Chromosome Location: 10q21-q24
Pathway: Amine ligand-binding receptors, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem;
Function: G-protein coupled receptor activity; neurotransmitter receptor activity; receptor activity; serotonin receptor activity; signal transducer activity;

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