Recombinant Human ID4 ID4-28592TH

Recombinant Human ID4

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Recombinant Human ID4

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Cat.No. : ID4-28592TH
Product Overview : Recombinant fragment corresponding to amino acids 60-110 of Human ID4with a proprietary tag, predicted MWt 31 kDa
Description : Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins (Pagliuca et al.
Protein length : 51 amino acids
Molecular Weight : 31.240kDa inclusive of tags
Source : Wheat germ
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.79% Tris HCl, 0.31% Glutathione
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : PALCLQCDMNDCYSR LRRLVPTIPPNKKVS KVEILQHVIDYILDL QLALET
Sequence Similarities : Contains 1 basic helix-loop-helix (bHLH) domain.
Gene Name : ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein [ Homo sapiens ]
Official Symbol : ID4
Synonyms : ID4; inhibitor of DNA binding 4, dominant negative helix-loop-helix protein; DNA-binding protein inhibitor ID-4; bHLHb27;
Gene ID : 3400
mRNA Refseq : NM_001546
Protein Refseq : NP_001537
MIM : 600581
Uniprot ID : P47928
Chromosome Location : 6p22.3
Pathway : Id Signaling Pathway, organism-specific biosystem; TGF-beta signaling pathway, organism-specific biosystem; TGF-beta signaling pathway, conserved biosystem;
Function : RNA polymerase II transcription factor binding; protein binding; transcription corepressor activity;

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