Recombinant Human IMPA2, His-tagged

• Cat.No.: IMPA2-29492TH
• Product Overview: Recombinant full length Human IMPA2 with an N terminal His tag ; predicted mwt: 33.5 kDa

Specification

• Description: This locus encodes an inositol monophosphatase. The encoded protein catalyzes the dephosphoylration of inositol monophosphate and plays an important role in phosphatidylinositol signaling. This locus may be associated with susceptibility to bipolar disorder.
• Protein length: 288 amino acids
• Conjugation: HIS
• Molecular Weight: 33.500kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 2mM DTT, pH 8
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MKPSGEDQAA LAAGPWEECF QAAVQLALRA GQIIRKALTE EKRVSTKTSA ADLVTETDHL VEDLIISELR ERFPSHRFIA EEAAASGAKC VLTHSPTWII DPIDGTCNFV HRFPTVAVSI GFAVRQELEF GVIYHCTEER LYTGRRGRGA FCNGQRLRVS GETDLSKALV LTEIGPKRDP ATLKLFLSNM ERLLHAKAHG VRVIGSSTLA LCHLASGAAD AYYQFGLHCW DLAAATVIIR EAGGIVIDTS GGPLDLMACR VVAASTREMA MLIAQALQTI NYGRDDEK
• Sequence Similarities: Belongs to the inositol monophosphatase family.

Gene Information

• Gene Name: IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 [ Homo sapiens ]
• Official Symbol: IMPA2
• Synonyms: IMPA2; inositol(myo)-1(or 4)-monophosphatase 2; inositol monophosphatase 2
• Gene ID: 3613
• mRNA Refseq: NM_014214
• Protein Refseq: NP_055029
• MIM: 605922
• Uniprot ID: O14732
• Chromosome Location: 18p11.2
• Pathway: D-myo-inositol (1,4,5)-trisphosphate degradation, conserved biosystem; Inositol phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, conserved biosystem; Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 =>
• Function: hydrolase activity; inositol monophosphate phosphatase activity; metal ion binding; protein homodimerization activity