Recombinant Human KAT2A, His-tagged
Cat.No. : | KAT2A-29886TH |
Product Overview : | Recombinant full length Human KAT2A / GCN5 with an N termianl His tag; 477 amino acids with the tag; predicted MWt: 51.1 kDa. |
- Specification
- Gene Information
- Related Products
Description : | KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al. |
Protein length : | 427 amino acids |
Conjugation : | HIS |
Molecular Weight : | 51.100kDa inclusive of tags |
Source : | E. coli |
Tissue specificity : | Expressed in all tissues tested, with most abundant expression in ovary. |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | pH: 8.00Constituents:0.08% DTT, 40% Glycerol, 1.17% Sodium chloride, 0.03% EDTA, 0.32% Tris HCl |
Storage : | Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHHSSGLVPRGSHMGGGS NSSLSLDSAGAEPMPGEKRTLPENL TLEDAKRLRVMGDIPMELVNEVMLT ITDPAAMLGPETSLLSANAARDETA RLEERRGIIEFHVIGNSLTPKANRR VLLWLVGLQNVFSHQLPRMPKEYIA RLVFDPKHKTLALIKDGRVIGGICF RMFPTQGFTEIVFCAVTSNEQVKGY GTHLMNHLKEYHIKHNILYFLTYAD EYAIGYFKKQGFSKDIKVPKSRYLG YIKDYEGATLMECELNPRIPYTELS HIIKKQKEIIKKLIERKQAQIRKVY PGLSCFKEGVRQIPVESVPGIRETG WKPLGKEKGKELKDPDQLYTTLKNL LAQIKSHPSAWPFMEPVKKSEAPDY YEVIRFPIDLKTMTERLRSRYYVTR KLFVADLQRVIANCREYNPPDSEYC RCASALEKFFYFKLKEGGLIDK |
Sequence Similarities : | Belongs to the GCN5 family.Contains 1 bromo domain.Contains 1 N-acetyltransferase domain. |
Gene Name : | KAT2A K(lysine) acetyltransferase 2A [ Homo sapiens ] |
Official Symbol : | KAT2A |
Synonyms : | KAT2A; K(lysine) acetyltransferase 2A; GCN5 general control of amino acid synthesis 5 like 2 (yeast) , GCN5L2; histone acetyltransferase KAT2A; GCN5; PCAF b; |
Gene ID : | 2648 |
mRNA Refseq : | NM_021078 |
Protein Refseq : | NP_066564 |
MIM : | 602301 |
Uniprot ID : | Q92830 |
Chromosome Location : | 17q12-q21 |
Pathway : | C-MYC pathway, organism-specific biosystem; E2F transcription factor network, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; |
Function : | H3 histone acetyltransferase activity; N-acetyltransferase activity; chromatin binding; histone acetyltransferase activity; contributes_to histone acetyltransferase activity; |
Products Types
◆ Recombinant Protein | ||
KAT2A-058H | Recombinant Human KAT2A Protein, His-tagged | +Inquiry |
KAT2A-2352H | Recombinant Human KAT2A Protein, His-tagged | +Inquiry |
KAT2A-005H | Recombinant Human KAT2A Protein, His-tagged | +Inquiry |
KAT2A-2132H | Recombinant Human KAT2A protein, GST-tagged | +Inquiry |
KAT2A-18H | Recombinant Human KAT2A Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
KAT2A-290HCL | Recombinant Human KAT2A HEK293T cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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