Recombinant Human KDM5A
Cat.No. : | KDM5A-29894TH |
Product Overview : | Recombinant fragment of Human KDM5A / Jarid1A / RBBP2 with proprietary tag, 36.63kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein. |
Protein length : | 100 amino acids |
Molecular Weight : | 36.630kDa inclusive of tags |
Source : | Wheat germ |
Biological activity : | useful for Antibody Production and Protein Array |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.31% Glutathione, 0.79% Tris HClNote: Glutathione is reduced |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | KVEPEVLSTDTQTSPEPGTRMNILP KRTRRVKTQSESGDVSRNTELKKLQ IFGAGPKVVGLAMGTKDKEDEVTRR RKVTNRSDAFNMQMRQRKGTLSVNF |
Sequence Similarities : | Belongs to the JARID1 histone demethylase family.Contains 1 ARID domain.Contains 1 JmjC domain.Contains 1 JmjN domain.Contains 3 PHD-type zinc fingers. |
Gene Name : | KDM5A lysine (K)-specific demethylase 5A [ Homo sapiens ] |
Official Symbol : | KDM5A |
Synonyms : | KDM5A; lysine (K)-specific demethylase 5A; JARID1A, jumonji, AT rich interactive domain 1A , Jumonji, AT rich interactive domain 1A (RBBP2 like) , RBBP2, retinoblastoma binding protein 2; lysine-specific demethylase 5A; |
Gene ID : | 5927 |
mRNA Refseq : | NM_001042603 |
Protein Refseq : | NP_001036068 |
MIM : | 180202 |
Uniprot ID : | P29375 |
Chromosome Location : | 12p11 |
Function : | DNA binding; chromatin binding; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen in; |
Products Types
◆ Recombinant Protein | ||
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KDM5A-597H | Recombinant Human KDM5A Protein (437-603 aa), His-SUMO-tagged | +Inquiry |
KDM5A-4782M | Recombinant Mouse KDM5A Protein, His (Fc)-Avi-tagged | +Inquiry |
KDM5A-8594M | Recombinant Mouse KDM5A Protein | +Inquiry |
KDM5A-683H | Recombinant Human KDM5A Protein, DDK-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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