Recombinant Human KDM5A Protein, DDK-tagged

• Cat.No.: KDM5A-683H
• Product Overview: Recombinant Human KDM5A fused with DDK tag at C-terminal was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression.
• Source: HEK293 cells
• Species: Human
• Tag: DDK
• Form: 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol.
• Molecular Mass: 192 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: KDM5A lysine (K)-specific demethylase 5A [ Homo sapiens ]
• Official Symbol: KDM5A
• Synonyms: KDM5A; lysine (K)-specific demethylase 5A; JARID1A, jumonji, AT rich interactive domain 1A , Jumonji, AT rich interactive domain 1A (RBBP2 like) , RBBP2, retinoblastoma binding protein 2; lysine-specific demethylase 5A; histone demethylase JARID1A; retinoblastoma binding protein 2; retinoblastoma-binding protein 2; jumonji/ARID domain-containing protein 1A; Jumonji, AT rich interactive domain 1A (RBP2-like); Jumonji, AT rich interactive domain 1A (RBBP2-like); RBP2; RBBP2; RBBP-2; JARID1A
• Gene ID: 5927
• mRNA Refseq: NM_001042603
• Protein Refseq: NP_001036068
• MIM: 180202
• UniProt ID: P29375