"KLK6" Related Products


Recombinant Human KLK6

Cat.No.: KLK6-26891TH
Product Overview: Recombinant full length human Kallikrein 6 with proprietary tag, 51.8kDa.
Description: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimers disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
Source: E. coli
Tissue specificity: In fluids, highest levels found in milk of lactating women followed by cerebrospinal fluid, nipple aspirate fluid and breast cyst fluid. Also found in serum, seminal plasma and some amniotic fluids and breast tumor cytosolic extracts. Not detected in urin
Form: Lyophilised:500ul distilled water for reconstitution then 20mM HEPES, pH 7.0
Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM HEPES, pH 7.0
Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.Contains 1 peptidase S1 domain.
Gene Name: KLK6 kallikrein-related peptidase 6 [ Homo sapiens ]
Official Symbol: KLK6
Synonyms: KLK6; kallikrein-related peptidase 6; kallikrein 6 (neurosin, zyme) , protease, serine, 18 , PRSS9, PRSS18; kallikrein-6; Bssp; Klk7; neurosin;
Gene ID: 5653
mRNA Refseq: NM_001012964
Protein Refseq: NP_001012982
MIM: 602652
Uniprot ID: Q92876
Chromosome Location: 19q13.3
Pathway: Alpha-synuclein signaling, organism-specific biosystem;
Function: peptidase activity; protein binding; serine-type endopeptidase activity; serine-type endopeptidase activity;

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