Recombinant Human KLK6
Cat.No. : | KLK6-26891TH |
Product Overview : | Recombinant full length human Kallikrein 6 with proprietary tag, 51.8kDa. |
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Description : | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimers disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. |
Source : | E. coli |
Tissue specificity : | In fluids, highest levels found in milk of lactating women followed by cerebrospinal fluid, nipple aspirate fluid and breast cyst fluid. Also found in serum, seminal plasma and some amniotic fluids and breast tumor cytosolic extracts. Not detected in urin |
Form : | Lyophilised:500ul distilled water for reconstitution then 20mM HEPES, pH 7.0 |
Storage buffer : | Preservative: NoneConstituents: 10% Glycerol, 20mM HEPES, pH 7.0 |
Storage : | Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Belongs to the peptidase S1 family. Kallikrein subfamily.Contains 1 peptidase S1 domain. |
Gene Name : | KLK6 kallikrein-related peptidase 6 [ Homo sapiens ] |
Official Symbol : | KLK6 |
Synonyms : | KLK6; kallikrein-related peptidase 6; kallikrein 6 (neurosin, zyme) , protease, serine, 18 , PRSS9, PRSS18; kallikrein-6; Bssp; Klk7; neurosin; |
Gene ID : | 5653 |
mRNA Refseq : | NM_001012964 |
Protein Refseq : | NP_001012982 |
MIM : | 602652 |
Uniprot ID : | Q92876 |
Chromosome Location : | 19q13.3 |
Pathway : | Alpha-synuclein signaling, organism-specific biosystem; |
Function : | peptidase activity; protein binding; serine-type endopeptidase activity; serine-type endopeptidase activity; |
Products Types
◆ Recombinant Protein | ||
KLK6-9483H | Recombinant Human KLK6 Protein, His-tagged | +Inquiry |
KLK6-1742H | Active Recombinant Human KLK6 Protein, His-tagged | +Inquiry |
KLK6-690H | Recombinant Human KLK6 Protein, MYC/DDK-tagged | +Inquiry |
KLK6-079H | Recombinant Human KLK6 Protein, His-tagged | +Inquiry |
KLK6-1040H | Recombinant Human KLK6 protein(Met1-Lys244) | +Inquiry |
◆ Lysates | ||
KLK6-1559HCL | Recombinant Human KLK6 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionStudies have shown that Klk6 recombinant protein may be involved in the occurrence and progression of tumors, especially in pancreatic and gastric cancers.
The level of Klk6 recombinant protein in pregnant women may change due to the needs of fetal growth and development, and regular monitoring is required.
The current treatments for Klk6 recombinant protein mainly include gene therapy, protein replacement therapy, and drug therapy for trypsin activity.
Studies have shown that Klk6 recombinant protein may be associated with cardiovascular diseases, liver diseases, and lung diseases.
Klk6 recombinant protein is mainly involved in the digestive process in the human body, helping to break down proteins in food.
If the level of Klk6 recombinant protein is abnormal, the treatment may include the use of drugs or other special treatments, depending on the condition and the doctor's recommendation.
Customer Reviews (3)
Write a reviewWhen experimenting with the KLK6, clear and consistent results are available for easy data analysis and interpretation.
KLKKLK6 products are available in a wide range of specifications for experimental designs of different sizes and needs.
KLK6 has a long half-life and is able to maintain stability and reliability during experiments.
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