Recombinant Human KPNA4 Protein, GST-tagged

• Cat.No.: KPNA4-29909TH
• Product Overview: Recombinant human KPNA4 full-length ORF ( NP_002259.1, 1 a.a. - 521 a.a.) protein with GST-tag at N-terminal.

Specification

• Description: The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 84.3 kDa
• AA Sequence: MADNEKLDNQRLKNFKNKGRDLETM RRQRNEVVVELRKNKRDEHLLKRRN VPHEDICEDSDIDGDYRVQNTSLEA IVQNASSDNQGIQLSAVQAARKLLS SDRNPPIDDLIKSGILPILVHCLER DDNPSLQFEAAWALTNIASGTSEQT QAVVQSNAVPLFLRLLHSPHQNVCE QAVWALGNIIGDGPQCRDYVISLGV VKPLLSFISPSIPITFLRNVTWVMV NLCRHKDPPPPMETIQEILPALCVL IHHTDVNILVDTVWALSYLTDAGNE QIQMVIDSGIVPHLVPLLSHQEVKV QTAALRAVGNIVTGTDEQTQVVLNC DALSHFPALLTHPKEKINKEAVWFL SNITAGNQQQVQAVIDANLVPMIIH LLDKGDFGTQKEAAWAISNLTISGR KDQVAYLIQQNVIPPFCNLLTVKDA QVVQVVLDGLSNILKMAEDEAETIG NLIEECGGLEKIEQLQNHENEDIYK LAYEIIDQFFSSDDIDEDPSLVPEA IQGGTFGFNSSANVPTEGFQF
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: KPNA4
• Official Symbol: KPNA4 karyopherin subunit alpha 4 [ Homo sapiens (human) ]
• Synonyms: KPNA4; karyopherin subunit alpha 4; QIP1; SRP3; IPOA3
• Gene ID: 3840
• mRNA Refseq: NM_002268
• Protein Refseq: NP_002259
• MIM: 602970
• UniProt ID: O00629