"IL13RA2" Related Products

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Recombinant Human Interleukin 13 Receptor, Alpha 2

Cat. No.: IL13RA2-1652H
Description: Interleukin 13 receptor alpha 2, also known as IL13RA2 and CD213A2, binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. IL13RA2 serves as a dominant negative inhibitor or a decoy receptor for IL-13. IL-13Ralpha2 is a promising target for ovarian cancer therapy, and the soluble form of IL-13R may be a possible surrogate marker for disease monitoring. IL13RA2 signaling during prolonged inflammation is also an important therapeutic target for the prevention of TGF-beta(1)-mediated fibrosis.
Molecular Weight: The predicted molecular weight of Recombinant Human IL-13 Rα2 is Mr 65 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 74 kDa.
Source: NSO Cells.
State Of Matter: Lyophilized.
Purity: >90% by SDS Page and analyzed by silver stain.
Endotoxin: <1.0 EU/µg as determined by the LAL method.
Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name: IL13RA2 interleukin 13 receptor, alpha 2 [ Homo sapiens ]
Synonyms: IL13RA2; interleukin 13 receptor, alpha 2; CT19; IL-13R; IL13BP; CD213A2; OTTHUMP00000023871; cancer/testis antigen 19; interleukin 13 binding protein; interleukin 13 receptor alpha 2 chain; IL-13 receptor; CD213a2; IL13R; OTTHUMP00000023871; CD213a2 antigen; Interleukin-13-binding protein
Gene ID: 3598
mRNA Refseq: NM_000640
Protein Refseq: NP_000631
MIM: 300130
UniProt ID: Q14627
Chromosome Location: Xq13.1-q28
Pathway: Jak-STAT signaling pathway
Function: cytokine receptor activity; receptor activity

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