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Recombinant Human LECT1

Cat.No.: LECT1-29939TH
Product Overview: Recombinant fragment of Human LECT1 with N terminal proprietary tag, 38kDa.
Description: This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.
Molecular Weight: 38.000kDa
Source: E. coli
Form: Lyophilised:Add 100ul of distilled water.
Storage buffer: pH: 6.80Constituents:1.58% Tris HCl, 3.09% DTT, 4% SDS, 0.2% Bromophenol blue, 20% Sucrose
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Gene Name: LECT1 leukocyte cell derived chemotaxin 1 [ Homo sapiens ]
Official Symbol: LECT1
Synonyms: LECT1; leukocyte cell derived chemotaxin 1; multiple myeloma tumor suppressor 1 , MYETS1; leukocyte cell-derived chemotaxin 1; CHM I; CHM1; chondromodulin;
Gene ID: 11061
mRNA Refseq: NM_001011705
Protein Refseq: NP_001011705
MIM: 605147
Uniprot ID: O75829
Chromosome Location: 13q14.3

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