"MAPK12" Related Products


Recombinant Human MAPK12

Cat.No.: MAPK12-31377TH
Product Overview: Recombinant full-length human SAPK3 with a N-terminal tag.
Description: Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes.
Tissue specificity: Highly expressed in skeletal muscle and heart.
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.Contains 1 protein kinase domain.
Gene Name: MAPK12 mitogen-activated protein kinase 12 [ Homo sapiens ]
Official Symbol: MAPK12
Synonyms: MAPK12; mitogen-activated protein kinase 12; SAPK3; ERK6; p38gamma; PRKM12; SAPK 3;
Gene ID: 6300
mRNA Refseq: NM_002969
Protein Refseq: NP_002960
MIM: 602399
Uniprot ID: P53778
Chromosome Location: 22q13.3
Pathway: Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; CDO in myogenesis, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem;
Function: ATP binding; MAP kinase activity; magnesium ion binding; nucleotide binding; protein binding;

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