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Recombinant Human MAPRE2, His-tagged

Cat.No. : MAPRE2-27378TH
Product Overview : Recombinant full-length Human EB2 with a N terminal His tag. 347 amino acids with a predicted MWt 39.2 kDa including tag.
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  • Gene Information
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Description : The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. The function of this protein is unknown; however, its homology suggests involvement in tumorigenesis of colorectal cancers and proliferative control of normal cells. This gene may belong to the intermediate/early gene family, involved in the signal transduction cascade downstream of the TCR. Alternative splicing results in multiple transcript variants.
Protein length : 327 amino acids
Conjugation : HIS
Molecular Weight : 39.200kDa inclusive of tags
Source : E. coli
Tissue specificity : Expressed in different tumor cell lines. Up-regulated in activated B- and T-lymphocytes.
Form : Liquid
Purity : by SDS-PAGE
Storage buffer : pH: 8.00Constituents:0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride, 0.02% DTT
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHHSSGLVPRGSHMPGPT QTLSPNGENNNDIIQDNNGTIIPFR KHTVRGERSYSWGMAVNVYSTSITQ ETMSRHDIIAWVNDIVSLNYTKVEQ LCSGAAYCQFMDMLFPGCISLKKVK FQAKLEHEYIHNFKLLQASFKRMNV DKVIPVEKLVKGRFQDNLDFIQWFK KFYDANYDGKEYDPVEARQGQDAIP PPDPGEQIFNLPKKSHHANSPTAGA AKSSPAAKPGSTPSRPSSAKRASSS GSASKSDKDLETQVIQLNEQVHSLK LALEGVEKERDFYFGKLREIELLCQ EHGQENDDLVQRLMDILYASEEHEG HTEEPEAEEQAHEQQPPQQEEY
Sequence Similarities : Belongs to the MAPRE family.Contains 1 CH (calponin-homology) domain.Contains 1 EB1 C-terminal domain.
Gene Name : MAPRE2 microtubule-associated protein, RP/EB family, member 2 [ Homo sapiens ]
Official Symbol : MAPRE2
Synonyms : MAPRE2; microtubule-associated protein, RP/EB family, member 2; microtubule-associated protein RP/EB family member 2; APC binding protein EB1; EB1; EB2; RP1;
Gene ID : 10982
mRNA Refseq : NM_001143826
Protein Refseq : NP_001137298
MIM : 605789
Uniprot ID : Q15555
Chromosome Location : 18q12.1
Function : microtubule binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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