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Recombinant Human Lipopolysaccharide Binding Protein

Cat. No. : LBP-1661H
Description : Lipopolysaccharide binding protein, also known as LBP, is a soluble acute phase secretory protein that binds to bacterial lipopolysaccharide (LPS) to elicit immune responses by presenting the LPS to important cell surface pattern recognition receptors called CD14 and TLR4. LBP is a major mediator of the lethal effects of endotoxemia.
Molecular Weight : The predicted molecular weight of Recombinant Human LBP is Mr 51 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 55-60 kDa.
Source : NSO Cells.
State Of Matter : Lyophilized.
Purity : >97% by SDS Page and analyzed by silver stain.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name : LBP lipopolysaccharide binding protein [ Homo sapiens ]
Synonyms : LBP; lipopolysaccharide binding protein; MGC22233; lipopolysaccharide-binding protein; LPS-binding protein; OTTHUMP00000030965
Gene ID : 3929
mRNA Refseq : NM_004139
Protein Refseq : NP_004130
MIM : 151990
UniProt ID : P18428
Chromosome Location : 20q11.23-q12
Pathway : Toll-like receptor signaling pathway; Signaling in Immune system
Function : Gram-negative bacterial cell surface binding; Gram-positive bacterial cell surface binding; cell surface binding; lipid binding; lipopolysaccharide binding; lipoteichoic acid binding; receptor binding

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