Recombinant Human MPO, GST-tagged

• Cat.No.: MPO-29360TH
• Product Overview: Recombinant fragment with GST tag corresponding to amino acids 621-745 of Human Myeloperoxidase; 125 amino acids, 40kDa.

Specification

• Description: Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain.The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils.
• Conjugation: GST
• Source: E. coli
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the peroxidase family. XPO subfamily.

Gene Information

• Gene Name: MPO myeloperoxidase [ Homo sapiens ]
• Official Symbol: MPO
• Synonyms: MPO; myeloperoxidase
• Gene ID: 4353
• mRNA Refseq: NM_000250
• Protein Refseq: NP_000241
• MIM: 606989
• Uniprot ID: P05164
• Chromosome Location: 17q21.3-q23
• Pathway: C-MYB transcription factor network, organism-specific biosystem; Folate Metabolism, organism-specific biosystem; IL23-mediated signaling events, organism-specific biosystem; Phagosome, organism-specific biosystem; Phagosome, conserved biosystem
• Function: chromatin binding; heme binding; heparin binding; metal ion binding; oxidoreductase activity