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Recombinant Human MTPN, His-tagged

Cat.No. : MTPN-28770TH
Product Overview : Recombinant full length Human Myotrophin with a N terminal His tag. 138 amino acids with a predicted MWt 15 kDa including tag.
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  • Gene Information
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Description : The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3 end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease.
Protein length : 118 amino acids
Conjugation : HIS
Molecular Weight : 15.000kDa inclusive of tags
Source : E. coli
Tissue specificity : Ubiquitous.
Form : Liquid
Purity : >90% by SDS-PAGE
Storage buffer : pH: 8.00Constituents:0.24% Tris, 10% Glycerol
Storage : Please see Notes section
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MCDKEFMWAL KNGDLDEVKD YVAKGEDVNR TLEGGRKPLH YAADCGQLEI LEFLLLKGAD INAPDKHHIT PLLSAVYEGH VSCVKLLLSK GADKTVKGPD GLTAFEATDN QAIKALLQ
Sequence Similarities : Belongs to the myotrophin family.Contains 3 ANK repeats.
Gene Name : MTPN myotrophin [ Homo sapiens ]
Official Symbol : MTPN
Synonyms : MTPN; myotrophin; GCDP; granule cell differentiation protein; MYOTROPHIN; V 1;
Gene ID : 136319
mRNA Refseq : NM_145808
Protein Refseq : NP_665807
MIM : 606484
Uniprot ID : P58546
Chromosome Location : 7q33-q35

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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