Recombinant Human MYL9, His-tagged

• Cat.No.: MYL9-30270TH
• Product Overview: Recombinant full length Human MYL9 with an N terminal His tag ; predicted mwt: 21.9kDa

Specification

• Description: Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene.
• Protein length: 172 amino acids
• Conjugation: HIS
• Molecular Weight: 21.900kDa
• Source: E. coli
• Tissue specificity: Smooth muscle tissues and in some, but not all, nonmuscle cells.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 100mM Sodium chloride, 1mM DTT, pH 8
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MSSKRAKAKT TKKRPQRATS NVFAMFDQSQ IQEFKEAFNM IDQNRDGFID KEDLHDMLAS LGKNPTDEYLEGMMSEAPGP INFTMFLTMF GEKLNGTDPE DVIRNAFACF DEEASGFIHE DHLRELLTTM GDRFTDEEVD EMYREAPIDK KGNFNYVEFTRILKHGAKDK DD
• Sequence Similarities: Contains 3 EF-hand domains.

Gene Information

• Gene Name: MYL9 myosin, light chain 9, regulatory [ Homo sapiens ]
• Official Symbol: MYL9
• Synonyms: MYL9; myosin, light chain 9, regulatory; myosin, light polypeptide 9, regulatory; myosin regulatory light polypeptide 9; LC20; MLC2; MRLC1; myosin regulatory light chain 1; myosin regulatory light chain 2; smooth muscle isoform; MYRL2
• Gene ID: 10398
• mRNA Refseq: NM_006097
• Protein Refseq: NP_006088
• MIM: 609905
• Uniprot ID: P24844
• Chromosome Location: 20q11.23
• Pathway: Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; Leukocyte transendothelial migration, organism-specific biosystem
• Function: calcium ion binding; structural constituent of muscle