Recombinant Human NEDD8, His-tagged

• Cat.No.: NEDD8-29619TH
• Product Overview: Recombinant full length Human NEDD8 fused to a His tag at the N-terminal; 113 amino acids, 12.8kDa

Specification

• Description: NEDD8 is a ubiquitin-like molecule, that can be covalently conjugated to cellular proteins in a similar way to that of ubiquitin. GST-NEDD8 may be used to identify proteins that interact with human NEDD8.
• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Highly expressed in heart, skeletal muscle, spleen, thymus, prostate, testis, ovary, colon and leukocytes.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 50mM Sodium chloride, 20mM Tris HCl, 0.5mM DTT, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMLI KVKTLTGKEI EIDIEPTDKV ERIKERVEEK EGIPPQQQRL IYSGKQMNDE KTAADYKILG GSVLHLVLAL RGG
• Sequence Similarities: Belongs to the ubiquitin family.

Gene Information

• Gene Name: NEDD8 neural precursor cell expressed, developmentally down-regulated 8 [ Homo sapiens ]
• Official Symbol: NEDD8
• Synonyms: NEDD8; neural precursor cell expressed, developmentally down-regulated 8; Nedd 8
• Gene ID: 4738
• mRNA Refseq: NM_006156
• Protein Refseq: NP_006147
• MIM: 603171
• Uniprot ID: Q15843
• Chromosome Location: 14q11.2
• Pathway: p53 pathway, organism-specific biosystem
• Function: ubiquitin protein ligase binding