"NEK2" Related Products

Expand

Recombinant Human NEK2

Cat.No. : NEK2-29279TH
Product Overview : Recombinant full length NEK2 protein (Human), was expressed by baculovirus in Sf9 insect cells using a N-terminal tag, MW 76kDa.
Description : This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene.
Tissue specificity : Isoform 1 and isoform 2 are expressed in peripheral blood T-cells and a wide variety of transformed cell types.
Form : Liquid
Purity : >90% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.Contains 1 protein kinase domain.
Gene Name : NEK2 NIMA (never in mitosis gene a)-related kinase 2 [ Homo sapiens ]
Official Symbol : NEK2
Synonyms : NEK2; NIMA (never in mitosis gene a)-related kinase 2; serine/threonine-protein kinase Nek2; HsPK 21; NEK2A; NLK1;
Gene ID : 4751
mRNA Refseq : NM_001204182
Protein Refseq : NP_001191111
MIM : 604043
Uniprot ID : P51955
Chromosome Location : 1q32-q42
Pathway : Cell Cycle, Mitotic, organism-specific biosystem; Centrosome maturation, organism-specific biosystem; FOXM1 transcription factor network, organism-specific biosystem; G2/M Transition, organism-specific biosystem; Loss of Nlp from mitotic centrosomes, organism-specific biosystem;
Function : ATP binding; metal ion binding; nucleotide binding; protein binding; protein kinase activity;

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.