|Product Overview :
||Recombinant full length NEK2 protein (Human), was expressed by baculovirus in Sf9 insect cells using a N-terminal tag, MW 76kDa.
||This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene.
|Tissue specificity :
||Isoform 1 and isoform 2 are expressed in peripheral blood T-cells and a wide variety of transformed cell types.
||>90% by SDS-PAGE
|Storage buffer :
||Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
||Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
|Sequence Similarities :
||Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.Contains 1 protein kinase domain.