Recombinant Human NEK6

• Cat.No.: NEK6-29622TH
• Product Overview: Recombinant full length NEK6 protein (Human), was expressed by baculovirus in Sf9 insect cells using a N-terminal tag, MW 63kDa.

Specification

• Description: The protein encoded by this gene is a kinase required for progression through the metaphase portion of mitosis. Inhibition of the encoded protein can lead to apoptosis. This protein also can enhance tumorigenesis by suppressing tumor cell senescence. Several transcript variants encoding a few different isoforms have been found for this gene.
• Tissue specificity: Ubiquitous, with highest expression in heart and skeletal muscle.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.Contains 1 protein kinase domain.

Gene Information

• Gene Name: NEK6 NIMA (never in mitosis gene a)-related kinase 6 [ Homo sapiens ]
• Official Symbol: NEK6
• Synonyms: NEK6; NIMA (never in mitosis gene a)-related kinase 6; serine/threonine-protein kinase Nek6; putative serine threonine protein kinase; SID6 1512
• Gene ID: 10783
• mRNA Refseq: NM_001145001
• Protein Refseq: NP_001138473
• MIM: 604884
• Uniprot ID: Q9HC98
• Chromosome Location: 9q33.3-q34.11
• Function: ATP binding; kinesin binding; magnesium ion binding; nucleotide binding; protein binding