Recombinant Human NFIC

• Cat.No.: NFIC-30377TH
• Product Overview: Recombinant fragment corresponding to the proline-rich activation domain of human NFIC with proprietary tag.

Specification

• Description: The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Source: E. coli
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the CTF/NF-I family.Contains 1 CTF/NF-I DNA-binding domain.

Gene Information

• Gene Name: NFIC nuclear factor I/C (CCAAT-binding transcription factor) [ Homo sapiens ]
• Official Symbol: NFIC
• Synonyms: NFIC; nuclear factor I/C (CCAAT-binding transcription factor); NFI; nuclear factor 1 C-type; CTF; CTF5; NF I
• Gene ID: 4782
• mRNA Refseq: NM_001245002
• Protein Refseq: NP_001231931
• MIM: 600729
• Uniprot ID: P08651
• Chromosome Location: 19p13.3
• Pathway: FOXA1 transcription factor network, organism-specific biosystem; RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription, organism-specific biosystem; RNA Polymerase III Abortive And Retractive Initiation, organism-specific biosystem; RNA Polymerase III Transcription, organism-specific biosystem; RNA Polymerase III Transcription Termination, organism-specific biosystem
• Function: DNA binding; sequence-specific DNA binding transcription factor activity